情绪调节:从神经回路到跨诊断视角
Carmen Morawetz1, Florian J Hemetsberger1, Angela R Laird2
1Department of Psychology, University of Innsbruck, Austria.
Neuroscience and biobehavioral reviews
|November 30, 2024
概括
情绪调节显示出独特的大脑模式,与研究领域标准 (RDoC) 领域不同,并且在精神疾病中始终与背中介前额叶皮层联系在一起,支持其跨诊断性质.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 认知科学 认知科学
背景情况:
- 情绪调节在精神病理学中至关重要,但其跨诊断地位仍在争论中.
- 现有的框架,如研究领域标准 (RDoC),对精神疾病进行分类,但情绪调节的位置尚不清楚.
- 了解情绪调节的神经基础是其作为跨诊断构造的潜力的关键.
研究的目的:
- 通过检查其神经基础来确定情绪调节是否是一种跨诊断构造.
- 将情绪调节的神经相关物与现有的RDoC域进行比较.
- 在精神疾病中的情绪调节期间识别常见的大脑活动模式.
主要方法:
- 使用了两步元分析方法.
- 步骤1:基于坐标的元分析重新分析了十项先前关于RDoC领域和健康成年人的情绪调节的元分析数据.
- 步骤2:全面的元分析检查了临床人群与健康对照人群中情绪调节的神经模式.
主要成果:
- 情绪调节与RDoC领域重叠,特别是认知和社会领域,但显示出不同的神经模式,涉及下部和中部前部转移.
- 背中介前额叶皮层在各种精神疾病中始终参与情绪调节.
- 这些发现支持RDoC框架内和跨疾病的情绪调节的独特神经支.
结论:
- 情绪调节表现出一种独特的神经基础,支持其被指定为跨诊断结构.
- 背中中前额叶皮层在各种疾病中的持续参与凸显了它在情绪调节中的重要性.
- 认识到情绪调节的跨诊断性质可以改进诊断标准,并为改善心理健康结果提供量身定制的治疗策略.
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