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Updated: Jun 6, 2025

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替代NADH脱酶:一个复杂的I备份,药物标,以及线粒体基因治疗的工具

Dmytro V Gospodaryov1

  • 1Department of Biochemistry and Biotechnology, Vasyl Stefanyk Precarpathian National University, 57 Shevchenka, 76018, Ivano-Frankivsk, Ukraine.

Biochimica et biophysica acta. Bioenergetics
|November 30, 2024
PubMed
概括

第二种类型的NADH脱酶 (NDH-2) 模仿复合物I,但缺乏质子送. 研究表明,NDH-2有可能通过各种机制治疗复杂I类缺陷并延长寿命.

关键词:
低氧/低氧化/低氧化线粒体疾病是线粒体疾病.昆诺隆是一种诺.罗斯曼的折叠方式第二种类型的NADH脱酶.铁 - 硫集群的铁 - 硫集群.

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