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控制牙周围牙周炎的瘤患者的根管感染
Kaline Romeiro1, Luciana F Gominho2, Danielle D Voigt1
1Postgraduate Program in Dentistry, University of Grande Rio (UNIGRANRIO), Rio de Janeiro, Rio de Janeiro, Brazil.
Journal of endodontics
|November 30, 2024
概括
化学机械制剂和内药物显著减少了癌症患者的根运河细菌. 治疗的有效性与对照组相似,在细菌负载或特定物种反应方面没有显著差异.
科学领域:
- 牙周内科医院 牙周内科医院 牙周内科医院
- 在瘤学瘤学.
- 微生物学 微生物学
背景情况:
- 接受抗瘤治疗的癌症患者通常具有免疫力受损,增加对感染的易感性.
- 在这些患者的牙周炎需要有效地管理根管中的细菌负载.
研究的目的:
- 评估化学机械制剂和内药物的有效性,以减少癌症患者的根运河细菌.
- 评估这些患者中链球菌和动菌菌种的患病率,水平和治疗反应.
主要方法:
- 瘤和对照患者的牙周炎的根通道使用旋转仪器,酸盐 (NaOCl) 灌和氧化药物治疗.
- 细菌学样本在化学机械制备前和后以及在内药物后被采集.
- 量化实时聚合酶链反应 (qPCR) 使用16S rRNA基因测定评估了总体细菌,链球菌和行动细菌.
主要成果:
- 化学机械制剂和内药物显著降低了总细菌负载 (S1-S2和S1-S3,P < .01).
- 虽然细菌数量从S2减少到S3,但这在统计学上并不显著 (P > .05).
- 在瘤和对照组之间没有观察到细菌数量,流行率或物种反应的显著差异.
结论:
- 结合化学机械制剂和内药物治疗方案,有效地减少了癌症患者感染根管中的细菌种群.
- 治疗结果与非癌症患者的治疗结果相似,表明在治疗尖端牙周炎方面具有相似的疗效.
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