用于通过乳清蛋白分离物-纳诺基丁复合体协而进行益生菌封装的微囊和药片的制备和表征
Mengxin Luo1, Le Ma1, Yuxi Guo1
1School of Chemistry and Chemical Engineering, Guangzhou University, Guangzhou 510006, PR China.
International journal of biological macromolecules
|December 1, 2024
概括
这项研究探讨了使用纳米基 (基纳米晶,基纳米纤维,基纳米圈) 与乳清蛋白分离物用于益生菌微囊. 这些微囊增强了Lactobacillus casei的活力,形成了稳定,持续释放的片.
科学领域:
- 材料科学 材料科学 材料科学
- 生物技术是生物技术.
- 食品科学 食品科学 食品科学
背景情况:
- 纳米基,包括基纳米晶 (CNC),基纳米纤维 (CNF) 和基纳米圈 (CNS),呈现基于合成的独特特性.
- 乳清蛋白分离物 (WPI) 是用于封装应用的常见生物聚合物.
- 有效封装益生菌,如乳杆菌casei (L. casei) 对于他们的生存和有效性至关重要.
研究的目的:
- 研究CNC,CNF和CNS在与WPI的复杂协中用于益生菌微囊制造的使用.
- 评估纳米-WPI微囊对L. casei活力和分娩的影响.
- 评估使用这些微囊制造压缩益生菌补充剂的潜力.
主要方法:
- 通过WPI和三种类型的纳米 (CNC,CNF,CNS) 之间的复杂协制造微囊.
- 在WPI-纳米基因矩阵中封装Lactobacillus casei (L. casei).
- 微囊性质的表征,包括益生菌活力和结构完整性.
- 将含有益生菌的微囊加工成压缩片.
主要成果:
- CNC,CNF和CNS表现出不同的形态,但都通过静电相互作用形成了带有WPI的正电荷的微囊.
- 用L.casei封装产生了一种保护性外,显著提高了益生菌的生存能力和殖民地形成单位数量.
- 与未含益生菌的微囊相比,带有益生菌的微囊形成了强大的片,具有更好的保护和持续释放特性.
结论:
- 纳米胺配方在基于WPI的复杂协中有效用于益生菌封装.
- 开发的微囊为L. casei.提供了更好的保护和生存能力.
- 这种方法为创建具有持续释放性质的先进,压缩益生菌补充剂提供了一种新的方法.
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