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简要报告:基于甲基化的ctDNA序列监测与NSCLC的免疫疗法反应相关

Angela Hsiao1, Brian Woodward1, Patrick Ye2

  • 1University of California San Diego, La Jolla, CA.

Clinical lung cancer
|December 1, 2024
PubMed
概括

一种基于甲基化的新型循环瘤DNA (ctDNA) 试验在预测非小细胞肺癌 (NSCLC) 免疫治疗反应方面表现有希望. 在治疗开始后早期测量的瘤甲基化得分 (TMS) 与无进展生存相关.

关键词:
基于抗PD1的检查点抑制剂.液体活检液体活检甲基循环瘤DNA 甲基循环瘤DNA非小细胞肺癌非小细胞肺癌在现实世界中,进步是自由的生存.

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Tumor Immunotherapy01:27

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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