精液中的SARS-CoV-2:一个多中心前性研究和文献综述
Giovanni Cochetti1, Michele Del Zingaro1, Giuseppe Maiolino2
1Department of Medicine and Surgery, Urology Clinic, University of Perugia, Perugia, Italy.
Basic and clinical andrology
|December 1, 2024
概括
这项研究发现,在男性的精液中没有发现SARS-CoV-2 (严重急性呼吸系统综合征冠状病毒2),这些男性有活跃或过去的COVID-19感染. 精液质量和性功能保持稳定,表明病毒对男性生殖健康没有重大影响.
科学领域:
- 病毒学 病毒学
- 生殖医学 生殖医学
- 传染性疾病 传染性疾病
背景情况:
- 男性精液中SARS-CoV-2的存在仍然是公共卫生和生殖问题的关键问题.
- 之前的研究在精液中检测到SARS-CoV-2时产生了相互矛盾的结果.
- 这项研究解决了围绕精液中病毒流放的不确定性.
研究的目的:
- 调查男性的精液样本中存在SARS-CoV-2的存在,这些样本来自有活跃感染的男性和那些有COVID-19病史的人.
- 评估SARS-CoV-2感染对精液质量和性/泌尿功能的影响.
- 审查有关精液中SARS-CoV-2检测的现有文献.
主要方法:
- 一项多中心前性研究招募了65名成年男性 (15名活跃感染,50名康复).
- 在精液样本上进行RT-PCR测试以检测SARS-CoV-2.
- 进行了精液分析,生殖器/性症状评估以及尿道/勃起功能得分 (IPSS,IIEF-5).
主要成果:
- 从活跃或康复组的任何精液样本中都没有检测到SARS-CoV-2.
- 两组之间没有观察到精液质量的统计学上显著差异.
- 尿路和勃起功能保持稳定,在感染阶段没有显著变化.
结论:
- 在经历急性感染的男性或从COVID-19中恢复过来的男性的精液中无法检测到SARS-CoV-2.
- COVID-19感染似乎不会显著影响精子参数或性/尿功能.
- 这些发现有助于了解SARS-CoV-2对生殖健康的长期影响.
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