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Jiawei Zhu¹, Ruiyi Yan², Jing Shen¹

¹Department of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

Asia-Pacific journal of clinical oncology

|December 2, 2024

概括

术后辅助放射治疗显著改善了上皮层癌患者的局部控制,降低了复发率. 这种治疗对于那些患这种罕见癌症的风险较高的人来说至关重要.

科学领域:

在瘤学瘤学.
内分泌学在内分泌学.
手术瘤学手术瘤学

背景情况:

皮上腺癌 (ACC) 是一种罕见的内分泌恶性瘤.
ACC具有很高的局部复发和转移的倾向.
有效的辅助疗法对于改善患者的治疗结果至关重要.

研究的目的:

评估术后辅助放射治疗对ACC患者结局的影响.
为了比较接受辅助放射治疗的患者和单独接受手术的患者之间的局部复发率和存活率.
确定辅助放射治疗在管理ACC中的作用.

主要方法:

对131名接受治疗切除的ACC患者的回顾性分析.
患者被分为两组:手术加辅助放射治疗 (n=15) 和单独手术 (n=30).
瘤分期使用了欧洲上腺瘤研究网络 (ENSAT) 系统.

主要成果:

辅助放射治疗显著降低了局部复发率 (20%比60%,p <0.05).
在放射治疗组,3年后无局域生存率显著高于放射治疗组 (77%vs38.1%,p<0.05).
两组之间没有观察到总体或无复发生存时间的显著差异.

结论:

术后辅助放射治疗有效地改善了对上腺皮层癌的局部控制.
辅助放射治疗应被认为是关键的治疗方式,特别是在高风险的ACC患者.
进一步的研究可能会探索其对远程复发和整体存活率的影响.

关键词:

作为辅助剂的放射治疗.上皮层癌 (adrenocortical carcinoma) 是一种上皮层癌.当地的控制控制.辐射疗法的疗效.瘤切除切除瘤的切除

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