在儿科和年轻成年人中,从心房动和心房动引起的血栓栓塞并发症:多中心研究
Robert Whitehill1,2, Allison C Hill3, Shankar Baskar4
1Department of Cardiology, Children's Healthcare of Atlanta, Atlanta, Georgia, USA.
Journal of cardiovascular electrophysiology
|December 2, 2024
概括
血栓塞栓并发症发生在患有心房 (AFib) 或心房 (AFl) 的年轻患者中,通常与结构性心脏病有关. 心转动后的随访事件很少发生,抗凝剂实践各不相同.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 电子生理学 电子生理学
- 血栓形成的研究研究
背景情况:
- 在儿童群体中,心房动 (AFib) 和心房动 (AFl) 不常见.
- 关于AFib/AFl的年轻患者的血栓栓塞并发症和抗凝药的数据有限.
研究的目的:
- 确定患有AFib或AFl的儿科和年轻成人患者中血栓栓塞并发症的发生率.
- 评估这个人口群体当前的抗凝血做法.
主要方法:
- 25岁以下患者的多中心回顾性队列研究.
- 包括2000-2019年间患有AFib/AFl的患者,但不包括心脏手术30天内患的患者.
主要成果:
- 在210名患者 (平均年龄17岁) 中,发生了311次AFib/AFl发作.
- 12个发作 (3.9%) 与血栓相关,主要是患有结构性心脏病 (SHD),心肌病或心室功能障碍的患者.
- 在预测血栓时,CHADSVASc评分的效用有限.
- 转心后血栓栓塞事件很少发生;抗凝策略在出院后有所不同.
结论:
- 血栓栓塞栓并发症是患有AFib/AFl的年轻患者的风险,特别是那些患有潜在心脏病的患者.
- 在这个人群中,CHADSVASc评分不是血栓栓塞风险的可靠预测指标.
- 需要进一步的研究来规范AFib/AFl.的年轻患者的抗凝策略.
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