与Mycoplasma genitalium感染相关的特征
Johnathan M Sheele1, Kara Bragg1
1Emergency Medicine, Mayo Clinic, Jacksonville, USA.
Cureus
|December 2, 2024
概括
在急诊室 (ED) 测试Mycoplasma genitalium (M. genitalium) 很少发生,但阳性结果很常见. 风险因素包括非白人种族,特定年龄组,婚姻状况和尿等同感染.
科学领域:
- 传染性疾病 传染性疾病
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 性传播感染 (STIs) 在美国急诊室 (EDs) 普遍存在.
- 关于ED环境中的Mycoplasma genitalium (M. genitalium) 患病率和风险因素的数据有限.
- 本研究研究了M. genitalium在机构层面的流行病学,特别是ED内部的流行病学.
研究的目的:
- 确定急诊室患者中M. genitalium感染的患病率和风险因素.
- 描述与ED中M. genitalium相关的流行病学和实验室发现.
- 为了比较M. genitalium检测和ED中的感染率与其他医疗机构的感染率.
主要方法:
- 从2014年10月到2023年9月的梅奥诊所企业数据的回顾性分析.
- 纳入标准:年龄在12-120岁的患者,有研究授权,并进行淋病,克拉米迪亚,三虫和M. genitalium的测试.
- 统计分析包括后勤回归来确定重大风险因素.
主要成果:
- 在332,619次接触中,M.生殖器测试发生在1.7%;1.8%的受测者呈阳性 (n=103).
- 自2020年以来,ED中的M.生殖器检测增加了,但仍然是STI检测的<1%.
- 有关M. genitalium的重要危险因素包括非白人种族 (OR 2.33),45-101岁 (OR 0.16),36-44岁 (OR 0.47),已婚/生活伴侣状态 (OR 0.27),ED测试 (vs.住院/门诊),以及尿液等离子体共感染 (OR 3.19).
结论:
- 在ED患者中,M. genitalium很少被测试,但阳性测试与感染高度相关.
- 非白人种族,特定年龄的人口统计数据,婚姻状况和Ureaplasma联合感染是M. genitalium.的确定的风险因素.
- 在ED环境中对M. genitalium进行进一步的研究和有针对性的测试策略是合理的.
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