探索尼亚摄入对心血管结果的影响:使用NHANES数据 (2003-2018) 进行全面分析
Lishi Shao1, Aihua Zhi1, Manning Li2
1Department of Radiology, Fuwai Yunnan Cardiovascular Hospital, 650102 Kunming, Yunnan, China.
Reviews in cardiovascular medicine
|December 2, 2024
概括
较高的氨酸摄入量与心血管疾病和全因死亡率的降低有关. 这种益处在整体人群中,特别是女性中观察到,但在男性中没有.
科学领域:
- 营养科学 营养科学
- 心血管健康 心血管健康
- 流行病学 流行病学
背景情况:
- 素消费与心血管结果之间的关联尚未得到充分证实.
- 了解氨酸对心血管疾病 (CVD) 发病率和死亡率的影响对于公共卫生至关重要.
研究的目的:
- 调查饮食中素摄入量与心血管疾病发病率之间的相关性.
- 检查素消费与全因和心血管疾病特异性死亡率之间的关系.
主要方法:
- 分析了80312名参与国家健康和营养检查调查 (2003-2018) 的数据.
- 参与者根据尼亚摄入量分为四分之一.
- 用于评估与死亡率和患病率的关联的权重考克斯回归和后勤回归模型.
主要成果:
- 在总人口中,较高的素摄入量 (Q4与Q1) 与全因死亡率 (HR:0.82) 和心血管疾病死亡率 (OR:0.80) 的降低有关.
- 在摄入较高酸的女性 (HR:0.78) 中,观察到所有原因死亡率的显著降低,但在男性中没有.
- 尼亚摄入量与女性心血管疾病死亡率的负面关联在摄入量较高的组 (Q3,Q4) 中.
结论:
- 增加氨酸消费与心血管疾病风险降低和全因死亡率相关.
- 氨酸的心脏保护作用似乎是性别特异性的,使女性比男性更受益.
- 进一步的研究可能会阐明尼亚对男性和女性心血管健康的影响差异背后的机制.
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