身体活动,VO2max和Visfatin对BMI和慢性炎症之间的关系的影响
Liqiang Su1,2, Shouzhi Wu3, Jinmei Fu4
1Physical Education of College, Jiangxi Normal University, Nanchang City, Jiangxi Province, People's Republic of China.
Diabetes, metabolic syndrome and obesity : targets and therapy
|December 2, 2024
概括
增加的体重指数 (BMI) 会使慢性炎症恶化. 身体活动 (PA) 和心肺健康 (VO2max) 减轻了这一点,而维斯法作为一个关键的调解者.
科学领域:
- 生理学 生理学 生理学
- 生物化学 生化学
- 公共卫生 公共卫生
背景情况:
- 体重指数 (BMI) 显示的肥胖是一个日益严重的公共卫生问题.
- 慢性炎症是许多疾病的重要危险因素.
- 了解BMI,炎症和生活方式因素之间的相互作用对于预防策略至关重要.
研究的目的:
- 研究BMI和慢性炎症之间的关系.
- 检查身体活动 (PA),心肺功能 (VO2max) 和visfatin在这种关系中的介导和相互作用作用.
主要方法:
- 119名参与者按BMI (肥胖,超重,正常体重) 分类.
- 对PA,VO2max,维斯法丁,hs-CRP和血液脂质的分析.
- 回归和协变分析以确定BMI对炎症和介导因素的影响.
主要成果:
- 体重指数升高与慢性炎症增加有显著的相关性.
- 压力,VO2max和视法与BMI的炎症作用相互作用.
- 维斯法廷约占BMI对慢性炎症的影响的19.35%.
结论:
- 较高的BMI会加剧慢性炎症.
- 增加的PA和VO2max可以减少慢性炎症.
- 维斯法丁在BMI-炎症途径中发挥着显著的积极调解作用.
更多相关视频
08:16Infrared Thermography for the Detection of Changes in Brown Adipose Tissue Activity
Published on: September 28, 2022
2.0K
06:22Isolation of Viable Adipocytes and Stromal Vascular Fraction from Human Visceral Adipose Tissue Suitable for RNA Analysis and Macrophage Phenotyping
Published on: October 27, 2020
3.8K
相关概念视频
Obesity
374
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
374
Exercise and Cardiovascular Response
734
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
734
Inflammation
52.6K
Overview
52.6K
Psychoneuroimmunology: Cardiovascular Disease
25
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
A key area of focus in PNI is the relationship between stress and coronary...
25
Inflammatory Response
1.8K
An inflammatory response is a localized, nonspecific immune reaction that occurs when a tissue is injured. It is characterized by redness, swelling, heat, and pain, which are commonly called the cardinal signs and symptoms of inflammation. Inflammation can sometimes result in a loss of function.
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
1.8K
Cholesterol: Significance and Regulation
504
Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
Considering cholesterol and...
504
