生物启发的微型和纳米结构系统用于癌症治疗
Rui Yang1, Bing Zhang2, Xiawei Fei3
1Department of Research Institute for Reproductive Medicine and Genetic Diseases, Wuxi Maternity and Child Health Care Hospital Jiangnan University Wuxi China.
生物启发的微型和纳米结构系统通过模仿自然来改善药物输送和瘤向来提供改进的癌症治疗. 本研究对这些系统进行了分类,讨论了它们的临床转化,并概述了未来的研究方向.
科学领域:
- 生物医学工程 生物医学工程
- 纳米技术纳米技术
- 在瘤学瘤学.
背景情况:
- 大自然为生物相容,瘤向和组织透系统提供了模型.
- 传统的癌症疗法在生物相容性,瘤透性和特异性方面存在局限性.
- 生物启发的微型和纳米结构系统解决了这些局限性,以提高治疗效率.
研究的目的:
- 系统地分类生物启发的微型和纳米结构系统用于癌症治疗.
- 阐明他们的灵感来源和设计原则.
- 讨论临床翻译,挑战和该领域的未来前景.
主要方法:
- 生物工程和生物结合技术被用来制造系统.
- 灵感来源于自然生物体的生物特性.
- 为这些系统开发了一个系统的分类框架.
主要成果:
- 生物灵感系统显示了增强的生物相容性和瘤向性.
- 这些系统显示了改善癌症治疗的潜力,并减少了副作用.
- 对于一些应用,在临床前和临床阶段取得了进展.
结论:
- 介绍了用于癌症治疗的生物灵感系统的全面分类.
- 该研究为研究和临床应用提供了理论框架和参考.
- 解决当前的挑战对于推进现场和临床翻译至关重要.
更多相关视频
14:20Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
Published on: June 13, 2014
07:54Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting
Published on: March 25, 2019
相关概念视频
Targeted Cancer Therapies
There are several types of targeted therapies against...
Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Combination Therapies and Personalized Medicine
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Tumor Immunotherapy
Drugs that Stabilize Microtubules
