结核患者感染C型肝炎病毒的风险:系统性审查和元分析
Neda Amoori1, Bahman Cheraghian2, Payam Amini3
1Abadan University of Medical Sciences, Abadan, Iran.
Iranian journal of public health
|December 2, 2024
概括
结核病 (TB) 患者面临型肝炎病毒 (HCV) 感染的风险增加. 早期对结核病患者的HCV查对于有效的治疗和公共卫生管理至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 结核病 (TB) 和型肝炎病毒 (HCV) 是全球重大健康挑战.
- 对结核病和HCV感染风险之间的关联有明确的理解,对于公共卫生战略至关重要.
研究的目的:
- 系统地审查和元分析结核病与C型肝炎病毒感染风险之间的关系.
主要方法:
- 在主要的科学数据库 (Google Scholar,Embase,Medline,Pubmed,Web of Science,Scopus) 中进行了全面的搜索.
- 在结核病患者中,使用随机效应模型计算HCV感染的聚合几率比率 (ORs).
- 使用I2测试,埃格尔和贝格的测试来评估异质性和出版偏差.
主要成果:
- 对13项研究的分析显示,结核病患者的HCV感染总体风险增加 (OR: 1.34,95% CI: 1.10-1.63).
- 与发达国家相比,发展中国家的风险更高 (OR: 1.95) (OR: 1.47).
- 在男性和65岁以上的个体中,HCV感染风险明显更高.
结论:
- 这些发现强调了对结核病患者进行HCV感染查的重要性.
- 确定结核病患者的HCV状况对于优化治疗结果和患者护理至关重要.
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