酸菜衍生的LAB菌株作为调节碳水化合物消化过程的潜在益生菌候选者,将细菌有机酸概况归因于抗糖尿病活性
Sujay S Huligere1, Chandana Kumari V B1, Shashank M Patil1
1Department of Biotechnology and Bioinformatics JSS Academy of Higher Education & Research Mysuru India.
Food science & nutrition
|December 2, 2024
概括
酸菜衍生乳酸细菌 (LAB) 显示出益生菌的潜力. 拉穆拉B48是一种突出的菌株,通过抑制关键酶和产生基酸,表现出优异的耐受性,抗菌,抗氧化和显著的抗糖尿病作用.
科学领域:
- 微生物学 微生物学
- 食品科学 食品科学 食品科学
- 生物技术是生物技术.
背景情况:
- 来自菜等发酵食品的乳酸细菌 (LAB) 菌株正在探索其对健康的益处.
- 益生菌的潜力与消化系统健康和管理糖尿病等代谢疾病有关.
- 油菜提供了强大且具有成本效益的益生菌候选人的来源.
研究的目的:
- 为了评估七种菜衍生的RAMULAB菌株的益生菌性质.
- 为了确定能够调节α-葡萄糖酶 (AG) 和α-氨基酶 (AM) 酶功能的菌株.
- 评估这些LAB菌株的抗糖尿病潜力及其分子相互作用.
主要方法:
- 使用16S核糖体RNA (rRNA) 测序识别RAMULAB菌株.
- 对胃肠道疾病的耐受性,粘附性质,抗微生物和抗氧化活性的评估.
- 对AG和AM酶的抑制的评估,加上分子相互作用的分析.
主要成果:
- 拉穆拉B48对酸性和胃肠道疾病 (分别≥97%和≥95%) 具有优越的弹性.
- 这种菌株表现出强大的粘附性质和强烈的抗菌活性,对抗食源性病原体.
- 拉穆拉B48显著抑制了酵母AG (59.55%) 和AM (67.42%),产生具有有前途的抗糖尿病作用的酸.
结论:
- RAMULAB48被认为是酸菜中的一个有前途的益生菌候选者.
- 这种菌株具有特殊的耐受性,粘附性,抗微生物,抗氧化剂和显著的抗糖尿病特性.
- 通过RAMULAB48的酸生产进一步支持其在糖尿病管理方面的潜力.
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