在清醒和睡眠期间的碎形运动活动:进入抑郁症最近和症状复发的窗口
O Minaeva1, H Riese1, S H Booij1,2
1Department of Psychiatry, University of Groningen, University Medical Center Groningen, Interdisciplinary Center Psychopathology and Emotion regulation, Groningen, The Netherlands.
Psychological medicine
|December 2, 2024
概括
运动活动中的碎形模式随着睡眠和抑郁而改变. 最近抑郁或缓解的个体的睡眠模式受到干扰可能预测抑郁症状的复发.
科学领域:
- 神经科学是一个神经科学.
- 时间生物学 时间生物学
- 复杂的系统复杂的系统.
背景情况:
- 健康的成年人表现出运动活动中的碎形模式,具有一致的时间相关性.
- 衰老和精神疾病破坏了这些自然的碎形模式.
研究的目的:
- 在睡眠-清醒周期中研究碎形运动活动模式的变化.
- 根据抑郁症诊断的近期情况,检查差异.
- 在抑郁发作之前和之后分析碎形模式的变化.
主要方法:
- 利用了来自两个队伍的378名个体的动作图数据.
- 使用缩放指数 (α) 来评估碎形模式的量化时间相关性.
- 采用线性混合模型来分析睡眠-清醒周期和抑郁状态对碎形模式的影响.
主要成果:
- 在所有个体中,碎形模式在清醒 (较大的α) 和睡眠 (较小的α) 之间有显著的差异.
- 碎形模式的睡眠-觉醒差异在最近抑郁的个体中减少.
- 经过缓解的个体经历了复发,在症状出现后的睡眠期间显示出改变的碎形模式.
结论:
- 睡眠期间的碎形运动活动模式与抑郁症状的复发有关.
- 这些发现突出了特定患者群体中抑郁复发的潜在生物标志物.
更多相关视频
06:23A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice
Published on: September 22, 2020
5.3K
10:28Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
Published on: July 24, 2019
15.1K
相关概念视频
01:24Sleep-Wake Cycles
1.2K
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
1.2K
01:15REM Sleep Behavior Disorder
145
REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
RBD is significantly associated with...
145