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在一项随机试验中,在1型糖尿病的老年人中,自动胰岛素递送在驾驶过程中的效果
Steven Trawley1,2, Hye Jin Kwon1,3, Sara Vogrin1
1Department of Medicine, The University of Melbourne, Melbourne, Australia.
第一代自动化胰岛素输送系统 (AID) 改善了1型糖尿病 (T1D) 的老司机驾驶时的葡萄糖控制. 这项技术可以降低高血糖,而不会增加低血糖的风险,提高驾驶安全.
科学领域:
- 内分泌学和糖尿病技术 技术
- 老年医学 老年医学
- 运输安全运输安全
背景情况:
- 1型糖尿病 (T1D) 中的低血糖会影响驾驶性能.
- 对于糖尿病治疗支持驾驶过程中高血糖症的证据有限,特别是在老年人中.
- 目前的建议通常建议胰岛素治疗的司机的葡萄糖水平>5.0 mmol/L.
研究的目的:
- 为了比较第一代自动化胰岛素输送 (AID) 与传感器增强疗法,以控制T1D的老年人驾驶期间的血糖.
- 评估这些技术对驾驶安全参数的影响,包括高血糖和低血糖.
主要方法:
- 随机交叉试验涉及8名患有T1D的60岁以上的成年人.
- 在1894年的驾驶旅行中,使用了持续的葡萄糖监测 (CGM).
- 第一个代AID和传感器增强疗法之间的比较.
主要成果:
- 葡萄糖范围>5.0-10.0 mmol/L的时间在AID (100%) 与传感器增强 (81%;P=0.033) 相比显著更大.
- 与传感器增强 (6.4%;P=0.006) 相比,在AID期间发生的CGM>16.7 mmol/L的旅行较少 (3.5%).
- 两种系统之间CGM<3.9 mmol/L或系统警报没有显著差异.
结论:
- 第一代AID有效降低T1D老年人的高血糖驾驶,而不会增加低血糖.
- 针对AID系统的专用"驾驶模式"设置可以进一步提高安全性,并最大限度地减少驾驶员的分心.
- 这项技术在改善该群体的驾驶安全方面表现有前途.
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