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Assays for the Identification of Novel Antivirals against Bluetongue Virus
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作为阿尔法病毒病毒复制抑制剂的4 - 替代的2 - 二胺

Atefeh Garzan1, S Kaleem Ahmed1, Nicole N Haese2

  • 1Scientific Platforms Division, Southern Research, 2000 ninth Avenue South, Birmingham, Alabama 35205, United States.

Journal of medicinal chemistry
|December 2, 2024
PubMed
概括

研究人员开发了一种新化合物,N-(4-(3-((4-cyanophenyl) amino) phenyl)thiazol-2-yl)-2-(methylthio) nicotinamide (26),用于对抗奇孔尼亚病毒 (CHIKV). 这种强大的抑制剂显示出显著的抗病毒活性和改善的稳定性.

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