微型中的纳米:食品传播病原体传播和病变发生的新概念
Yue Liu1, Xuchuan Ma1, Monica Cazzaniga2,3
1Food Microbiology, Wageningen University & Research, Wageningen, The Netherlands; email: yue1.liu@wur.nl, tjakko.abee@wur.nl.
Annual review of food science and technology
|December 2, 2024
概括
这项研究探讨了食物传播病原体中的新型纳米级组件,如菌体和细胞外囊泡,影响它们的生存和传播. 了解这些"纳米微"元素是改善食品安全和病原体控制的关键.
科学领域:
- 食品微生物学 食品微生物学
- 病原体生存机制 病原体生存机制
- 食品安全研究 食品安全研究
背景情况:
- 食物传播的病原体具有复杂的机制,可以在各种压力下生存.
- 传统的研究一直专注于宏观层面的适应,忽视纳米级组件.
- 了解病原体适应对于食物链传播和病原发生至关重要.
研究的目的:
- 突出影响食物传播病原体生存和毒性的新型纳米级组件.
- 在病原体研究中引入"纳米微"这一新兴领域.
- 重新评估实验室条件,研究适应性应激反应.
主要方法:
- 对最近对细菌菌体/菌体,细菌细胞外囊泡和细菌微区的洞察力进行了审查.
- 讨论影响病原体适应性的未经研究的食品相关基质.
- 分析饮食和微生物群对肠道殖民和宿主入侵的影响.
主要成果:
- 菌体,细胞外囊泡和微分区 (统称为"微中的纳米") 显著影响病原体的应激反应和生存.
- 特定的与食物相关的基质和宿主因素 (饮食,微生物群) 在病原体适应和毒性方面发挥着关键作用.
- 目前的实验室条件可能不能完全代表现场病原体适应应激反应.
结论:
- 新的纳米级组件及其相互作用对于食源病原体的适应性和毒性至关重要.
- 需要转向"纳米微"研究的范式转变,以全面了解食物传播病原体.
- 将"纳米在微"的见解与风险评估模型相结合,可以增强食品安全战略.
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