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核心针活检可以预测状腺癌手术前的预后

Jeong-Yeon Ji^1,2, Wonjae Cha^1,2, Young Ho Jung³

¹Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Seongnam, Korea.

Clinical and experimental otorhinolaryngology

|December 2, 2024

概括

手术前的核心针活检 (CNB) 可以改善状腺癌的诊断和预后. CNB的准确性高于细针吸收 (FNA),识别恶性瘤并指导患者的治疗结果.

科学领域:

在瘤学瘤学.
手术病理学手术病理学
诊断成像诊断成像诊断成像

背景情况:

唾液腺瘤带来了诊断上的挑战,往往导致意外的恶性瘤诊断后parotidectomy.
术前诊断的准确性对于适当的手术规划和患者管理至关重要.

研究的目的:

评估手术前核心针活检 (CNB) 的临床实用性,以诊断乳头腺癌在乳头切除术前.
评估腺癌患者中CNB发现的预后影响.

主要方法:

对615名患者进行了回顾性队列研究,这些患者接受了为原发性乳头瘤进行CNB和乳头切除术 (2003-2023年).
分析了102例恶性瘤病例的生存结果 (无疾病生存率).
在547名患者的单独队列中,CNB诊断指标与超声波引导细针吸收 (FNA) 相比较.

主要成果:

与精细针吸收 (FNA) 相比,核心针活检 (CNB) 显示了显著更高的灵敏度 (89.0%) 和负预测值 (97.6%).
恶性瘤的CNB诊断是减少无病生存时间的显著预测因素 (HR,8.20).
男性的性别也与预后较差有关 (HR,8.48).

结论:

手术前的核心针活检 (CNB) 对于预测癌预后非常有价值.
患有CNB诊断的恶性瘤的患者面临的预后比那些"不太恶性"诊断的患者更糟糕.
在检测腺癌方面,CNB比FNA具有更高的灵敏度.

关键词:

核心针活检活检核心针活检针头活检是用针头进行的.状腺是什么样子的这种新生体是 Parotid 新生体.唾液腺新生体唾液腺新生体

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