Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Bone Disorders01:29

Bone Disorders

3.4K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.4K
Bone Remodeling01:40

Bone Remodeling

38.1K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
38.1K
Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

2.8K
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
2.8K
What is the Skeletal System?01:02

What is the Skeletal System?

52.2K
Overview
52.2K
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

2.6K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
2.6K
Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

3.2K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
3.2K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Gravitational and mechanical forces shape mitochondrial translation.

Nature communications·2026
Same author

Trends in anti-osteoporosis pharmacotherapy and pharmacological initiation for secondary fracture prevention in Japan, 2017-2023.

Bone·2026
Same author

Oral bisphosphonates and risk of incident osteoarthritis in individuals with osteoporosis: a target trial emulation.

RMD open·2026
Same author

Corrigendum to Osteoarthritis risk associated with romosozumab compared with teriparatide in individuals with osteoporosis: A target trial emulation study Ann Rheum Dis 2025;84(11):1938-1947.

Annals of the rheumatic diseases·2026
Same author

Investigation of cartilage modification for controlling immune reaction against xenogeneic cartilage.

Regenerative therapy·2026
Same author

Nationwide trends and variations in reverse shoulder arthroplasty in Japan: national database analysis 2014-2023.

JSES international·2026

相关实验视频

Updated: Jun 6, 2025

Author Spotlight: Integrating Traditional Chinese Medicine with Modern Pharmacology and Genomics for Assessing Postmenopausal Osteoporosis in Mice
07:20

Author Spotlight: Integrating Traditional Chinese Medicine with Modern Pharmacology and Genomics for Assessing Postmenopausal Osteoporosis in Mice

Published on: August 23, 2024

443

[骨质疏松症] 这是什么?

Taku Saito1

  • 1Department of Orthopaedic Surgery, Sensory and Motor System Medicine, Graduate School of Medicine, The University of Tokyo.

No shinkei geka. Neurological surgery
|December 2, 2024
PubMed
概括
此摘要是机器生成的。

骨质疏松症显著增加骨折风险,特别是在由于平衡和力量受损而患有神经系统疾病的患者中. 早期风险评估和量身定制的治疗对于管理这种普遍的骨疾病至关重要.

更多相关视频

Estrogen-Like Effect of Bazi Bushen Capsule in Ovariectomized Rats
08:56

Estrogen-Like Effect of Bazi Bushen Capsule in Ovariectomized Rats

Published on: April 7, 2023

829
A Novel in vivo Gene Transfer Technique and in vitro Cell Based Assays for the Study of Bone Loss in Musculoskeletal Disorders
11:47

A Novel in vivo Gene Transfer Technique and in vitro Cell Based Assays for the Study of Bone Loss in Musculoskeletal Disorders

Published on: June 8, 2014

11.6K

相关实验视频

Last Updated: Jun 6, 2025

Author Spotlight: Integrating Traditional Chinese Medicine with Modern Pharmacology and Genomics for Assessing Postmenopausal Osteoporosis in Mice
07:20

Author Spotlight: Integrating Traditional Chinese Medicine with Modern Pharmacology and Genomics for Assessing Postmenopausal Osteoporosis in Mice

Published on: August 23, 2024

443
Estrogen-Like Effect of Bazi Bushen Capsule in Ovariectomized Rats
08:56

Estrogen-Like Effect of Bazi Bushen Capsule in Ovariectomized Rats

Published on: April 7, 2023

829
A Novel in vivo Gene Transfer Technique and in vitro Cell Based Assays for the Study of Bone Loss in Musculoskeletal Disorders
11:47

A Novel in vivo Gene Transfer Technique and in vitro Cell Based Assays for the Study of Bone Loss in Musculoskeletal Disorders

Published on: June 8, 2014

11.6K

科学领域:

  • 老年学是指老年学的学科.
  • 整形外科 整形外科 整形外科
  • 神经学 神经学

背景情况:

  • 骨质疏松症是最常见的骨疾病,增加骨折易感性.
  • 多种因素导致骨折风险,包括生活方式,遗传学和药物使用.
  • 神经系统疾病通过平衡障碍和肌肉力量降低而加剧风险,导致跌倒.

研究的目的:

  • 突出骨质疏松症和骨折风险的多方面的性质.
  • 强调神经疾病患者的脆弱性增加.
  • 强调风险评估和骨质疏松症管理中的专业治疗的重要性.

主要方法:

  • 对骨质疏松症风险因素的文献综述.
  • 分析神经系统疾病对跌倒和骨折风险的影响.
  • 讨论当前的骨质疏松症治疗策略和医生责任.

主要成果:

  • 骨折风险受到个人病史,生活方式选择,遗传学和药物的结合的影响.
  • 神经病患者的体力活动减少显著增加了跌倒和骨折的风险.
  • 有有效的,针对患者的骨质疏松症治疗方法可用.

结论:

  • 医生,包括神经外科医生等非专家,必须评估骨质疏松症和骨折风险.
  • 早期识别和干预是预防风险人群骨折的关键.
  • 与专家的合作确保了骨质疏松症的最佳管理.