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微质与脊髓损伤中的微环境的相互作用

A V Timofeeva1, E R Akhmetzyanova1, A A Rizvanov2

  • 1Kazan (Volga Region) Federal University, Kazan, Russia.

Neuroscience
|December 2, 2024
PubMed
概括

中枢神经系统 (CNS) 的免疫细胞微细胞在脊髓损伤 (SCI) 后表现出复杂的行为和相互作用. 了解它们的可塑性和微环境是调节它们对潜在治疗策略的亲和抗炎反应的关键.

关键词:
星球细胞是星球细胞.细胞外矩阵是细胞外矩阵.微质细胞中的微质细胞单细胞衍生的巨细胞.这些神经元是神经元.细胞 (Pericytes) 是一种细胞.脊髓损伤导致的脊髓损伤

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In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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