在ERAS®实施前和之后接受选择性结肠直肠手术的患者早期术后恢复的比较 - - 一个单一中心的三臂队列研究
Katharina Knab1, Leon Aurnhammer1, Sylvia Büttner2
1Department of Surgery, Medical Faculty Mannheim, University Medical Center Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, D-68167, Mannheim, Germany.
International journal of colorectal disease
|December 2, 2024
概括
手术后增强恢复 (ERAS®) 协议显著改善了结直肠手术后患者的康复. 实施ERAS®导致了更早的排便,增加了食物摄入量,减少了阿片类药物使用,证明了患者的良好结果.
科学领域:
- 结肠直肠手术 结肠直肠手术
- 手术恢复协议 手术恢复协议
背景情况:
- 手术后增强恢复 (ERAS®) 协议旨在优化患者的康复.
- 评估ERAS®对结直肠外科手术结果的影响对于临床实践至关重要.
研究的目的:
- 评估ERAS®协议在选择性结直肠手术后患者康复方面的有效性.
- 用PostopQRSTM工具分析患者的康复情况.
主要方法:
- 一个单一中心的研究比较了三个队列:两个追溯 (ERAS®前后) 和一个前性 (ERAS®后与PostopQRSTM).
- 在2020年6月至2022年2月期间,包括153名患者.
- 在德国临床试验登记册 (DRKS00026903) 进行前性注册.
主要成果:
- 实施ERAS®显著改善了肠道功能,口服食物摄入量,减少了阿片类药物使用和术后恶心和吐 (PONV).
- 在ERAS®后的队列中,98%的患者通过排泄实现了肠道运动或口腔的输出,而在ERAS®前的66% (p < 0.001).
- 术后第一天 (POD1) 固体食物摄入量较高,在ERAS®后队列中,阿片类药物使用量较低.
结论:
- 结肠直肠ERAS®的实施可以改善早期的流动性和早期的肠道排便.
- 增强的恢复协议减少了对阿片类药物的需求,并增加了POD1.1的固体食物摄入量.
- 在结直肠手术后,ERAS®协议与患者的良好康复有关.
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