树 (Cupressus torulosa),一种抗氧化多的来源:一个分析和药理学研究
Radhika Khanna1, H R Chitme2, Khushaboo Bhadoriya1
1Chemistry & Bioprospecting Division, Forest Research Institute, Dehradun, India.
Rapid communications in mass spectrometry : RCM
|December 2, 2024
概括
(Cupressus torulosa) 针显示出显著的抗氧化活性,为抗氧化压力提供了药物使用的潜力. 这项研究确定了关键的抗氧化化合物,为自然医学发展铺平了道路.
科学领域:
- 植物化学 植物化学
- 药理学 药理学是指药理学的学科.
- 自然产品 自然产品
背景情况:
- 树 (Cupressus torulosa) 是喜马拉雅的针叶树,它的空气部分有着传统的用途.
- 它的针具有已知的抗炎,抗,抗微生物和伤口愈合特性.
- 来自C. torulosa的抗氧化剂对于对抗各种疾病所涉及的氧化应激至关重要.
研究的目的:
- 为了评估Cupressus torulosa针的抗氧化潜力.
- 为了确定负责抗氧化活性的生物活性化合物.
- 探索C. torulosa提取物的制药和营养应用.
主要方法:
- 进行了体外,体内和体外测试.
- 生物化学估计包括总醇含量和总黄含量.
- 使用UPLC-QTOF-MS分析进行代谢物分析.
主要成果:
- 来自C. torulosa针的水性甲醇提取物表现出有前途的抗氧化活性.
- 乙酸乙烯分量显示出显著的自由基清除活性 (EC50 = 85.6μg/mL在DPPH试验中).
- UPLC-QTOF-MS确定了34种代谢物,包括乙酸乙酸部分中的10种关键抗氧化化合物.
结论:
- (Cupressus torulosa) 针是生物活性抗氧化剂的宝贵来源.
- 这些发现支持C. torulosa在制药和营养食品应用中的潜力.
- 进一步的研究可能会导致天然抗氧化剂的开发,用于与氧化压力相关的条件.
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