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评估局部橄叶提取物乳膜在治疗复发性唇疹治疗中的有效性:一项随机对照临床研究

Mai Adnan Gaizeh Al-Hallak¹, Jamileh Ali Hsaian², Abeer Ahmad Aljoujou³

¹Faculty of Dentistry, Oral Medicine Department, Damascus University, Damascus University, Damascus, Syria. maighallak@gmail.com.

Scientific reports

|December 2, 2024

概括

橄叶提取物 (OLE) 通过促进皮层更快脱落,在治愈复发性唇疹 (RHL) 病变方面具有显著的优势. 虽然疼痛缓解与阿西克洛维尔奶油相当,但OLE为RHL管理提供了一个有前途的替代方案.

科学领域:

口腔健康口腔健康
皮肤病学皮肤病学
植物疗法植物疗法

背景情况:

复发性口腔疹 (RHL) 影响全球三分之一的人口,导致疼痛的口腔病变.
目前的治疗方法可以控制症状,但可能有局限性.

研究的目的:

为了比较橄叶提取物 (OLE) 与阿西克洛维尔奶油在治疗RHL病变方面的疗效.
为了评估疼痛强度,完成疼痛愈合的时间,以及病变皮层的脱落.

主要方法:

一个随机的,三盲研究,涉及40名RHL患者.
参与者在五天内每天五次使用OLE或阿西克洛维尔奶油 (Veramid 5%).
疼痛和愈合指标在基线,48小时和7天被评估.

主要成果:

在OLE和阿西克洛维尔组之间没有观察到疼痛强度或完成疼痛愈合的时间的显著差异.
与阿西克洛维尔奶油 (P=0.040) 相比,橄叶提取物在统计学上显著地更快地脱落了病变皮层.

结论:

橄叶提取物 (OLE) 是一种潜在的替代性治疗选择,可以治疗复发性唇疹.
由于OLE的皮层脱落速度更快,这表明它对病变的解决有有益影响.

关键词:

亚环维尔 (acyclovir) 是一种药物.埃穆尔盖尔是一种乳.简单的疹病毒简单的病毒.橄叶提取物橄叶提取物经常出现的唇部疹.

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