相关实验视频

Updated: Aug 6, 2026

Automating ChIP-seq Experiments to Generate Epigenetic Profiles on 10,000 HeLa Cells
08:34

Automating ChIP-seq Experiments to Generate Epigenetic Profiles on 10,000 HeLa Cells

Published on: December 10, 2014

18.7K

EpiCHAOS:用于量化单细胞数据中的表观基因组异质性的指标

Katherine Kelly1,2, Michael Scherer1, Martina Maria Braun3

  • 1Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.

Genome biology
|December 2, 2024
PubMed
概括

我们开发了epICHAOS,这是一个新的指标,用于量化单细胞表观遗传学数据中的细胞对细胞表观遗传异质性. 这种工具揭示了对发育可塑性和癌症的洞察力,改善了瘤异质性分析.

关键词:
癌症 癌症 癌症 癌症染色是一种染色素.通过DNA甲基化.表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.异质性 异质性 异质性塑性是一种可塑性.单细胞表观遗传学 单细胞表观遗传学

更多相关视频

A Semiautomated ChIP-Seq Procedure for Large-scale Epigenetic Studies08:04

A Semiautomated ChIP-Seq Procedure for Large-scale Epigenetic Studies

Published on: August 13, 2020

3.3K
Reusable Single Cell for Iterative Epigenomic Analyses10:28

Reusable Single Cell for Iterative Epigenomic Analyses

Published on: February 11, 2022

1.3K

相关概念视频

Epistasis Analysis01:09

Epistasis Analysis

Although Mendel chose seven unrelated traits in peas to study gene segregation, most traits involve multiple gene interactions that create a spectrum of phenotypes. When the interaction of various genes or alleles at different locations influences a phenotype, this is called epistasis. Epistasis often involves one gene masking or interfering with the expression of another (antagonistic epistasis). Epistasis often occurs when different genes are part of the same biochemical pathway. The...