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Updated: May 12, 2026

Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection
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智能:使用标记基因辅助主题模型进行空间转录学解卷

Chen Xi Yang1,2, Don D Sin3,4, Raymond T Ng3,5,6

  • 1Centre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. yolanda.yang@hli.ubc.ca.

Genome biology
|December 2, 2024
PubMed
概括

空间转录组学方法往往缺乏单细胞分辨率. 新型解卷工具SMART准确地推断细胞类型和基因表达,优于现有增强生物洞察力的方法.

关键词:
解体解体是一种解体.半监督 半监督 半监督空间转录组学 空间转录组学主题模型 主题模型

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相关概念视频

DNA Microarrays02:34

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...