抗血栓治疗对小肠出血的影响:欧洲多中心回顾性研究
Lucia Scaramella1, Stefania Chetcuti Zammit2, Reena Sidhu3,4
1Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Clinical endoscopy
|December 3, 2024
概括
视频囊内镜 (VCE) 是安全的小肠出血 (SBB) 的评估. 抗血栓治疗不会影响诊断产量或出血率,这证实了这些患者的VCE安全性.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 内部医学 内部医学
背景情况:
- 小肠出血 (SBB) 是视频囊内镜 (VCE) 的首要指示.
- 抗血栓治疗对SBB的VCE诊断产量 (DY) 的影响仍然令人担忧.
- 了解这些影响对于优化患者管理至关重要.
研究的目的:
- 调查抗血栓治疗对SBB.患者VCE诊断产量和安全性的影响.
- 为了比较不同抗血栓治疗方案的患者和不接受这种治疗的患者之间的结果.
主要方法:
- 从2001年3月到2020年7月,在两个中心 (意大利米兰和英国谢菲尔德) 连续接受SBB的VCE患者的回顾性分析.
- 收集人口统计数据,临床参数,抗血栓药物治疗和VCE程序特征.
- 在不同抗血栓治疗组中评估VCE发现,诊断产量,完成率和明显出血率.
主要成果:
- 在957名SBB患者中,共进行了1052次VCE,总诊断收益率为50.6%.
- 在接受直接口服抗凝剂,其他抗凝剂,抗血小板治疗,单一治疗或联合抗血小板治疗的子组之间,没有观察到VCE完成率,发现或诊断产量的显著差异.
- 显露出血率在所有组中保持相似,包括对抗血栓使用者和非使用者之间的比较,以及单疗法和联合疗法之间的比较.
结论:
- 视频囊内镜是一种安全且具有临床影响力的程序,用于评估小肠出血.
- 抗血栓治疗,包括抗凝固剂和抗血小板药,不会对SBB的VCE的诊断产量或明显出血率产生不利影响.
- 在接受抗血栓治疗的患者中,可以安全地进行VCE,以评估小肠出血.
相关概念视频
Esophageal Varices-II: Clinical Features and Management
46
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
46
Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants
1.2K
Oral anticoagulants are vital tools in preventing and treating blood clotting disorders. This diverse class of medications can be categorized as vitamin K antagonists, exemplified by warfarin, and direct thrombin inhibitors (DTIs), such as dabigatran, as well as factor Xa inhibitors, including rivaroxaban.
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
1.2K
Anticoagulant Drugs: Low-Molecular-Weight Heparins
616
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
616
Antiplatelet Drugs: Prostaglandin Synthesis, P2Y12 and Glycoprotein IIb/IIIa Inhibitors
468
Antiplatelet drugs emerge as frontline defenders against the insidious threat of thromboembolic diseases, where abnormal clots obstruct vital blood vessels. These drugs stand as bulwarks, inhibiting platelet aggregation and clot formation, thereby mitigating the risk of life-threatening conditions like myocardial infarction, coronary artery disease, and thrombotic strokes.
Prostaglandin synthesis inhibitors, exemplified by the widely known aspirin, wield their power by irreversibly acetylating...
Prostaglandin synthesis inhibitors, exemplified by the widely known aspirin, wield their power by irreversibly acetylating...
468
Inflammatory Bowel Disease IV: Pharmacological Management
112
Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
Pharmacologic...
112
Inflammatory Bowel Disease V: Surgical Management
118
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
118


