与大麻戒断相关的精神病:系统审查和病例系列
Edward Chesney1,2,3, Thomas J Reilly2,3,4, Fraser Scott3
1Department of Addictions, King's College London, UK.
The British journal of psychiatry : the journal of mental science
|December 3, 2024
概括
突然停止大量使用大麻可以引发精神病. 大麻戒断可能会导致新的精神病发作或现有疾病的复发.
科学领域:
- 精神病学是一个精神病学.
- 神经科学是一个神经科学.
- 大麻研究 大麻研究
背景情况:
- 戒断大量使用大麻可能会导致戒断症状,如焦虑和失眠.
- 新出现的证据表明,大麻戒断和急性精神病发作之间存在联系.
- 大麻戒断综合征是一个公认的临床实体.
研究的目的:
- 调查大麻戒断与精神病之间的联系.
- 为了确定大麻戒断后发生的精神病的临床病例.
- 分析大麻戒断在引发或加剧精神疾病中的作用.
主要方法:
- 对案例报告和系列的系统文献审查.
- 对精神病医疗记录的大型电子数据库的分析.
- 包括多样化的研究设计,以捕捉相关的案例.
主要成果:
- 从21项研究中确定44名患有大麻戒断后精神病的个体.
- 在医疗记录中发现了68例额外的病例,包括首发精神病和复发性精神病.
- 每日大麻使用者突然停止使用是最受影响的.
- 在精神病后继续使用大麻显著增加了复发风险 (OR 13.9).
结论:
- 突然的大麻戒断可能会导致第一次精神病发作.
- 大麻戒断是精神病复发的潜在触发因素.
- 在大麻使用和戒断后,急性精神病症状可能会出现.
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