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Updated: Jun 6, 2025

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YAP1-MAML2融合驱动瘤发生并维持瘤生长

Wei Ni1,2,3, Mu Yu1,2, Rongqiang Yang1,2

  • 1Department of Molecular Genetics and Microbiology, University of Florida, Gainesville, FL 32610, USA.

Molecular therapy. Oncology
|December 3, 2024
PubMed
概括

YAP1-MAML2 (YM) 融合蛋白驱动癌症的开始和进展. 抑制YM/TEAD通路为YM阳性癌症提供了一个有前途的治疗策略.

关键词:
在TEAD/YAP1的转录中.在YAP1-MAML2核聚变过程中,融合基因瘤基因的融合瘤发生的发生因子.治疗目标是治疗的目标.

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