疼痛和压力之间的相互增强的动态:机制,影响和管理策略
Nour Aboushaar1,2, Natalia Serrano1
1Global Medical Affairs, Bayer HealthCare LLC, Whippany, NJ, United States.
Frontiers in pain research (Lausanne, Switzerland)
|December 3, 2024
概括
疼痛和压力共享重叠的机制,创造了一个恶性循环,使两种情况都变得更糟. 解决生物心理社会因素的整体方法对于有效的管理和改善福祉至关重要.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 公共卫生 公共卫生
背景情况:
- 疼痛和压力是影响生活质量和生产力的普遍情况.
- 它们共享复杂的生物和心理机制,经常在恶性循环中相互加剧.
- 如果不治疗,这些疾病可能会慢性化,导致严重的医疗费用和生产率下降.
研究的目的:
- 审查重叠的生理,认知和社会机制驱动疼痛-压力循环.
- 突出这一循环的临床影响,并倡导管理中的范式转变.
- 强调医疗保健专业人员需要提高意识.
主要方法:
- 关于共享疼痛和压力机制的科学文献的综述.
- 分析所涉及的生理,认知,行为和社会因素.
- 包括一个案例研究来说明循环的现实世界永恒化.
主要成果:
- 确定了重叠的关键机制:不适应性神经可塑性,神经内分泌功能障碍,慢性炎症,避免恐惧,超警,灾难化以及社会经济/环境因素.
- 证明了这些因素如何在疼痛和压力之间创造相互增强的动态.
- 通过一个案例研究来说明疼痛-压力循环的永恒性.
结论:
- 整体的管理策略,整合药物,心理和生活方式干预措施是必不可少的.
- 解决潜在的生物心理社会因素是打破疼痛压力循环的关键.
- 提高初级保健从业人员的意识可以改善患者的支持和结果.
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