低老年营养风险指数与美国老年人低认知功能之间的关联:一个横截面研究
Jiuling Liu1, Melysze Deanne Oorloff2, Adithya Nadella2
1Department of Neurology, Nanjing BenQ Medical Center, The Affiliated BenQ Hospital of Nanjing Medical University, Nanjing, China.
Frontiers in nutrition
|December 3, 2024
概括
低老年营养风险指数 (GNRI) 显示的营养不良与老年人认知功能较差有关. 这种关联在70岁及以上或有中风病史的人群中更为明显.
科学领域:
- 老年学是一门学科.
- 营养科学 营养科学
- 认知神经科学 认知神经科学
背景情况:
- 营养状况对于老龄人口的认知健康至关重要.
- 老年营养风险指数 (GNRI) 是评估老年人营养风险的有效工具.
- 认知能力下降是老年人群的一个重大问题,影响生活质量.
研究的目的:
- 调查老年营养风险指数 (GNRI) 与美国老年人的认知功能之间的关联.
- 为了确定GNRI测量的营养状况是否预测低认知功能的风险.
- 探索GNRI与其他因素 (如年龄,中风) 对认知结果的潜在相互作用.
主要方法:
- 从国家健康和营养检查研究 (NHANES) 的数据进行横截面分析.
- 参与者被分为正常营养 (>98 GNRI) 和营养不良 (≤98 GNRI) 组.
- 用CERAD单词列表学习,DSST,AFT和复合z-score来评估认知功能;用于分析的加权后勤回归.
主要成果:
- 总共分析了2925名老年人 (51.3%为女性),其中233人被确定为营养不良.
- 在所有测试领域 (CERAD W-L,AFT,DSST,复合z-score) 中,营养不良的个体表现出低认知功能的风险增加.
- 在特定的认知领域中,在低GNRI和中风史之间,以及在低GNRI和高级年龄 (≥70岁) 之间发现了显著的相互作用.
结论:
- 较低的GNRI水平与老年人认知功能下降有显著的关联.
- 由于营养不良而导致认知障碍的风险在老年人 (≥70岁) 和有中风病史的人群中特别高.
- 这些发现强调了营养评估和干预对于维持老年人群认知健康的重要性.
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