在特纳综合征中神经心理挑战的范围
Jacqueline I Fezza1, Srishti Rau2, Lauren Clary1,3
1The George Washington University School of Medicine and Health Sciences, Washington, DC, United States.
Frontiers in endocrinology
|December 3, 2024
概括
在特纳综合征 (TS) 中,正式的神经心理评估揭示了ADHD和焦虑等常见挑战. 早期查至关重要,尤其要注意基于型的潜在智商差异.
科学领域:
- 神经心理学 神经心理学
- 遗传学 是一个遗传学.
- 儿科 儿科 儿科
背景情况:
- 特纳综合征 (TS) 与显著的神经心理障碍有关.
- 在关键的发展过渡期间,建议对这些挑战进行查.
研究的目的:
- 详细说明在TS患者中进行正式神经心理评估的机构经验.
- 调查基于型的评估结果的潜在差异.
主要方法:
- 在2019年1月至2022年10月期间,对114名TS患者进行评估的回顾性图表审查.
- 使用SAS V9.4.4进行描述性统计分析.
主要成果:
- 38%的患者完成了神经心理评估,平均年龄为11.3岁.
- 在45,X型组中观察到较低的中位数全尺度智商 (FSIQ),尽管在调整后并不统计显著.
- 在26%的患者中诊断出注意力缺陷多动性障碍 (ADHD) 和焦虑障碍,还注意到特定的学习障碍 (数学) 和自闭症谱系障碍.
结论:
- 神经心理异常的高患病率凸显了TS中早期和一致的神经心理测试的必要性.
- 这些发现支持了多学科诊所内定制评估对特纳综合征管理的重要性.
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