血液动力学抑制对动脉支架后患者的认知功能的影响
Weidong Fan1,2, Kun Liu2, Xingyou Guo2
1Department of Vascular Surgery, Nanjing Drum Tower Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
概括
动脉支架 (CAS) 可以暂时降低认知功能,特别是当血液动力学抑郁症 (HD) 发生时. 预防HD对于中风患者来说至关重要,以改善中风后的认知恢复.
科学领域:
- 神经学 神经学
- 心血管外科心血管外科
- 认知科学 认知科学
背景情况:
- 动脉支架 (CAS) 是一种用于中风患者的手术.
- CAS对认知功能的影响,特别是关于血液动力学抑郁症 (HD) 的影响,需要进一步调查.
研究的目的:
- 为了评估CAS对中风患者认知功能的影响.
- 为了确定血液动力学抑郁症 (HD) 在CAS后对认知结果的影响.
主要方法:
- 分析了一组130名在2019年1月至2023年6月期间接受CAS的患者.
- 患者被分为血液动力学抑郁症 (HD) 和非HD组.
- 使用迷你心理状态检查 (MMSE) 和蒙特利尔认知评估 (MoCA) 在手术前和手术后1,3,6和12个月的得分来评估认知功能.
主要成果:
- 患HD的发生率为51.54% .
- 与非HD组相比,HD组在CAS后3,6和12个月表现出明显较低的MMSE和MoCA得分 (P<0.05).
- 在HD组中,注意力,计算和记忆受损,而非HD组在6个月和12个月后表现出认知能力的改善.
结论:
- CAS可以导致认知功能暂时下降,并有可能改善.
- 血液动力学抑郁症 (HD) 显著加剧认知障碍,并延长了CAS后的恢复.
- 预防HD对于优化中风患者进行CAS的认知结果至关重要.
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