在先天性静止夜盲症中,自然过程的折射误差:对近视治疗的影响
Mariëlle M F Poels1, Gerard C de Wit1, Mieke M C Bijveld1
1Bartiméus Diagnostic Center for Complex Visual Disorders, Zeist, The Netherlands.
Investigative ophthalmology & visual science
|December 3, 2024
概括
在患有先天性静止夜盲 (CSNB) 的儿童中,近视的进展在4岁后显著放缓. 这一发现对于评估这些患者的近视控制治疗至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 遗传学 是一个遗传学.
- 儿科 儿科 儿科
背景情况:
- 近视控制治疗在儿童中很常见,但在患有遗传性视网膜疾病 (IRDs) 的儿童中,其有效性尚不清楚.
- 在应用治疗之前,了解特定IRDs近视的自然进展是必不可少的.
研究的目的:
- 为了调查与先天性静止夜盲 (CSNB) 的儿童的折射误差的自然过程,舒伯特-博恩舍因类型.
- 建立评估近视控制干预措施在这个人群的基线.
主要方法:
- 追溯分析295个折射测量从127名患者的CSNB (CSNB1和CSNB2) 年龄在0-21岁.
- 排除之前接受过近视控制治疗的患者.
- 应用线性混合效应模型来分析折射误差的进展.
主要成果:
- 折射误差在幼儿时期迅速增加到近视.
- 4岁以后,近视的进展减缓到每年 -0.12二视度,直到15岁,之后它稳定了下来.
- 老年儿童近视的高患病率:100%的CSNB1和84%的CSNB2患者超过4岁是近视的.
结论:
- 患有CSNB的儿童的折射误差在4岁后显示出最小的变化.
- 在考虑对患有CSNB的儿童进行近视控制干预时,建议采取谨慎的方法.
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