相关实验视频

Updated: Jun 6, 2025

Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers

Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers

Published on: January 13, 2018

在接受关节置换手术的老年患者中,西普罗和普罗波之间的术后觉醒的比较:单盲,随机,受控试验

Dawei Yang¹, Jie Zhou², Luyu Sun¹

¹Department of Anesthesiology, Affiliated Hospital of Yangzhou University, University of Yangzhou, Yangzhou, China.

Minerva anestesiologica

|December 3, 2024

概括

与普罗波相比,西普罗在老年关节置换患者中延长了唤醒和输出时间. 虽然西普罗导致恢复时间更长,但它也减少了流体需求,增加了尿液输出.

科学领域:

麻醉学麻醉学
老年医学老年医学
手术护理手术护理

背景情况:

关节置换手术在老年患者中很常见.
麻醉的选择会影响术后恢复.
普罗波是一种广泛使用的麻醉剂.

研究的目的:

为了比较西普罗和普罗波对接受关节置换的老年患者手术后觉醒的影响.
评估二次恢复参数和麻醉要求.

主要方法:

随机对照试验与90名老年患者 (每组45名).
持续输注西普罗福尔与普罗波福尔用于麻醉诱导和维持.
主要结果:觉醒时间. 二次结局:呼吸恢复,输出时间,镇静得分,液体平衡和血管活性药物的使用.

主要成果:

齐普罗组的觉醒时间显著长 (11.0分 vs 7.4分),呼吸恢复时间 (9.9分 vs 5.9分) 和输出时间 (12.0分 vs 8.5分).
使用西普罗与减少液体补充 (728.9 vs 908.3 mL) 和增加尿液输出 (235.1 vs 173.5 mL) 相关.
与西普罗一起观察到更高的雷米芬坦尼尔剂量;没有观察到警觉或不良事件的显著差异.

结论:

与普罗波相比,在老年关节置换患者中服用西普罗会导致长时间的觉醒,呼吸恢复和输出时间.
西普罗的平均维持剂量为0.8 mg·kg^-1·h^-1.
尽管恢复时间较长,但西普罗在流体管理和尿液输出方面可能有好处.

更多相关视频

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

Assessing Changes in Volatile General Anesthetic Sensitivity of Mice after Local or Systemic Pharmacological Intervention

Assessing Changes in Volatile General Anesthetic Sensitivity of Mice after Local or Systemic Pharmacological Intervention

Published on: October 16, 2013

相关概念视频

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...

Stages of General Anesthesia

Stages of General Anesthesia

Various sedation levels offer significant advantages in facilitating procedural interventions for patients undergoing medical or invasive surgical procedures. These levels span from anxiolysis to general anesthesia, providing a spectrum of sedative effects to cater to specific patient needs. Anxiolysis reduces anxiety and is achieved through minimal sedation, enabling patients to remain awake and responsive while feeling more at ease during the procedure. This level can benefit minor...

General Anesthesia: Overview

General Anesthesia: Overview

Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...