Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Tumor Immunotherapy01:27

Tumor Immunotherapy

476
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
476
Cytotoxic T Cells-mediated Immune Response01:27

Cytotoxic T Cells-mediated Immune Response

846
Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...
846
Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

67.0K
Overview
67.0K
Cells of the Innate Immune Response01:28

Cells of the Innate Immune Response

1.5K
The innate immune response is an immediate and non-specific response against pathogens, acting swiftly to prevent the spread of infections. The primary cells involved in this response are phagocytes and natural killer (NK) cells.
Phagocytes
Phagocytes police the peripheral tissues by removing cellular debris and responding to the invasion of foreign substances or pathogens. Many phagocytes attack and remove microorganisms even before lymphocytes detect them. The human body has two general...
1.5K
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

7.5K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
7.5K
Special Features of Adaptive Immunity01:20

Special Features of Adaptive Immunity

748
The adaptive immune system, a crucial component of the overall immune response, offers a highly specialized defense against pathogens. It involves specific cell types and features, enabling it to combat infections effectively and efficiently.
The primary cell types involved in adaptive immunity are T cells and B cells. Each type has a unique role in defending the body against pathogens. T cells are responsible for cell-mediated immunity. They identify and eliminate infected cells directly,...
748

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Chimeric allergen receptor regulatory T cells suppress birch pollen allergic airway inflammation.

The Journal of experimental medicine·2026
Same author

Impact of physiological strain on lung epithelial cells by exposure to aerosolised quartz silica in a perfused bioreactor.

Frontiers in bioengineering and biotechnology·2026
Same author

Maternal Body Mass Index, Offspring Impaired Skin Barrier Function, Allergic Sensitization, and Bronchial Obstruction.

Allergy·2026
Same author

Pyrazinamide susceptibility testing in <i>Mycobacterium tuberculosis</i>: impact of false-positive BD MGIT 960 results and added value of sequencing for accurate diagnosis in a low-MDR-TB-incidence context.

Frontiers in cellular and infection microbiology·2026
Same author

Bemnifosbuvir and remdesivir inhibit tick-borne encephalitis virus infection in complementary in vitro and ex vivo disease models.

Antiviral research·2026
Same author

Referral pathway for adults with chronic cough in Switzerland from a Delphi-based consensus study.

Postgraduate medicine·2026
Same journal

Safety and Pharmacokinetic Data for Inhaled Administration of Nintedanib Dry Powder Inhalation for Treatment of Pulmonary Fibrotic Diseases.

Journal of aerosol medicine and pulmonary drug delivery·2026
Same journal

Selecting the Optimal Inhaler in Asthma: Respiratory and Peripheral Muscle Strength as Predictors of DPI and MDI Response.

Journal of aerosol medicine and pulmonary drug delivery·2026
Same journal

Usability of Levodopa Cyclops<sup>®</sup> Compared to INBRIJA<sup>®</sup> During an off Episode in Parkinson's Disease Patients.

Journal of aerosol medicine and pulmonary drug delivery·2026
Same journal

Design of Dry Powder Inhalers: 1. Does Size Matter?

Journal of aerosol medicine and pulmonary drug delivery·2026
Same journal

Design of Dry Powder Inhalers: 2. The Impact of Suboptimal Peak Inspiratory Flow Rates on Bronchodilation in Patients with Obstructive Lung Diseases.

Journal of aerosol medicine and pulmonary drug delivery·2026
Same journal

Inhaler Adherence and Treatment Behaviors in COPD: A Study from Both Sides of the Aegean Sea.

Journal of aerosol medicine and pulmonary drug delivery·2026
查看所有相关文章

相关实验视频

Updated: Jun 6, 2025

Non-Viral Engineering of Primary Human T Cells via Homology-Mediated End-Joining Targeted Integration of Large DNA Templates
06:10

Non-Viral Engineering of Primary Human T Cells via Homology-Mediated End-Joining Targeted Integration of Large DNA Templates

Published on: May 9, 2025

125

准免疫细胞的目标

Emilie Seydoux1, Kleanthis Fytianos1, Christophe von Garnier1

  • 1Department of Biomedical Research, University of Bern, Bern, Switzerland.

Journal of aerosol medicine and pulmonary drug delivery
|December 3, 2024
PubMed
概括
此摘要是机器生成的。

吸入的纳米粒子为肺免疫调节提供了有针对性的输送,有可能治疗或预防肺部疾病. 对纳米载体免疫调节效应的仔细分析对于开发有效的吸入疗法至关重要.

关键词:
树突细胞是一种树突细胞.免疫力是一种免疫力.免疫调节 免疫调节 免疫调节免疫疗法 免疫疗法吸入治疗是一种吸入疗法.纳米颗粒是一种纳米粒子.

更多相关视频

A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells
12:16

A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells

Published on: October 16, 2018

14.7K
Analysis of Human T Cell Activity in an Allogeneic Co-Culture Setting of Pre-Treated Tumor Cells
09:01

Analysis of Human T Cell Activity in an Allogeneic Co-Culture Setting of Pre-Treated Tumor Cells

Published on: March 7, 2025

290

相关实验视频

Last Updated: Jun 6, 2025

Non-Viral Engineering of Primary Human T Cells via Homology-Mediated End-Joining Targeted Integration of Large DNA Templates
06:10

Non-Viral Engineering of Primary Human T Cells via Homology-Mediated End-Joining Targeted Integration of Large DNA Templates

Published on: May 9, 2025

125
A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells
12:16

A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells

Published on: October 16, 2018

14.7K
Analysis of Human T Cell Activity in an Allogeneic Co-Culture Setting of Pre-Treated Tumor Cells
09:01

Analysis of Human T Cell Activity in an Allogeneic Co-Culture Setting of Pre-Treated Tumor Cells

Published on: March 7, 2025

290

科学领域:

  • 肺免疫学 肺免疫学
  • 纳米医学是一种纳米医学.
  • 药物输送系统是药物输送系统.

背景情况:

  • 呼吸道的大面积和薄薄的屏障促进了与吸入物质的相互作用.
  • 像上皮细胞,巨细胞和树突细胞这样的肺免疫细胞对于先天性和适应性免疫是至关重要的.
  • 这些前线免疫细胞表现出基于肺区的多样性特征,使它们成为吸入免疫调节剂的理想目标.

研究的目的:

  • 通过吸入探索纳米载体在肺免疫调节中的潜力.
  • 研究如何用纳米载体准特定的肺免疫细胞可以调节免疫反应.
  • 突出纳米载体在肺部疾病的预防和治疗策略中的作用.

主要方法:

  • 通过使用强有力的载体,准肺内的特定免疫能力细胞.
  • 调节免疫细胞-抗原相互作用,包括吸收,贩运,加工和呈现.
  • 利用纳米颗粒的沉积和向性质用于局部或全身免疫反应调节.

主要成果:

  • 纳米载体的吸入表明了预防和治疗应用的潜力.
  • 纳米粒子触发的免疫反应可以是免疫刺激性或免疫抑制性.
  • 针对特定的细胞群或肺部区块可以触发或调节免疫反应.

结论:

  • 纳米载体对肺免疫调节有希望,为治疗和预防肺部疾病提供有针对性的输送.
  • 彻底评估纳米载体的免疫调节,药理和毒理性质是必不可少的.
  • 跨学科的合作是设计和特征有效的吸入纳米载体的肺部应用的关键.