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Updated: Jun 6, 2025

Evaluation of T Follicular Helper Cells and Germinal Center Response During Influenza A Virus Infection in Mice
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Evaluation of T Follicular Helper Cells and Germinal Center Response During Influenza A Virus Infection in Mice

Published on: June 27, 2020

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CCR4+Tfh2细胞专门产生IL-4,在IgG4相关疾病中驱动病理反应

Mitsuhiro Akiyama1, Keiko Yoshimoto2, Hidekata Yasuoka3

  • 1Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan. mitsuaki@keio.jp.

Clinical and experimental rheumatology
|December 3, 2024
PubMed
概括

CCR4识别了产生Interleukin-4的Tfh2细胞,这些细胞在IgG4相关疾病 (IgG4-RD) 中升高. 这些细胞透到受影响的组织中,并且不是葡萄糖皮质类药物的有效目标,这可能解释了高复发率.

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Induction of Intestinal Inflammation by Adoptive Transfer of CBir1 TCR Transgenic CD4+ T Cells to Immunodeficient Mice

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