在成年人中,甲状腺刺激激素和身体脂肪的关联
Qin Sun1, Yixuan He2, Liang Yang1
1Yulin Hospital, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
PloS one
|December 3, 2024
概括
甲状腺刺激激素 (TSH) 与肥胖有关. 这项研究发现,TSH与成年人,特别是女性的总体脂肪具有积极的相关性,并显示了男性与腹部脂肪的U形联系.
科学领域:
- 内分泌学 在内分泌学.
- 代谢健康 代谢健康
- 肥胖问题研究研究
背景情况:
- 甲状腺刺激激素 (TSH) 与代谢功能障碍有关,包括肥胖.
- 了解TSH与肥胖的联系对于公共卫生至关重要.
- 特定的脂肪测量,如总脂肪百分比 (TPF),安卓脂肪百分比 (APF) 和骨脂肪百分比 (GPF) 需要调查.
研究的目的:
- 检查TSH水平与成年人肥胖指标之间的关联.
- 为了研究TSH与总体,安卓和骨体脂肪百分比的关系.
- 在TSH-肥胖关系中探索潜在的性别差异.
主要方法:
- 从NHANES (2007-2012) 对809名正常TSH的成年人 (≥20岁) 的分析.
- 多变量线性回归模型评估了TSH与TPF,APF和GPF的关联.
- 一般化的增材模型和光滑曲线探索了非线性关系,并进行了性别分层分析.
主要成果:
- 在整个成年人群中,TSH和TPF之间发现了显著的积极关联.
- 雌性在TSH和TPF,APF和GPF之间显示出显著的正相关性.
- 男人没有显著的线性TSH-肥胖相关性,但显示了TSH和APF之间的U形非线性关联.
结论:
- 在成年人中,TSH与总体脂肪具有积极的关联.
- 在TPF,APF和GPF的雌性中存在显著的TSH脂肪关系.
- 男性在TSH和腹部脂肪 (APF) 之间表现出独特的U形非线性关系.
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