美国抗癌药物定价趋势与竞争的影响,2014-20
Rena M Conti1, Claire Mcglave2, Meredith B Rosenthal3
1Rena M. Conti (rconti@bu.edu), Boston University, Boston, Massachusetts.
Health affairs (Project Hope)
|December 3, 2024
概括
抗癌药物价格在品牌药物上,但在仿制药物上下跌. 竞争提高了可负担性,但有限的仿制药可用性限制了癌症药物的这种好处.
科学领域:
- 卫生经济学 卫生经济学
- 药物经济学 药物经济学
- 瘤学 治疗学 治疗学
背景情况:
- 抗癌药物的成本上升对医疗保健支出产生影响,对医疗保健计划和患者来说都是如此.
- 了解价格动态和竞争对于管理瘤领域的医疗保健支出至关重要.
研究的目的:
- 分析抗癌药物的定价趋势.
- 评估市场竞争对这些价格的影响,包括仿制药和生物类似药的进入.
主要方法:
- 利用了185种抗癌药物的IQVIA数据 (2014年10月至2020年2月).
- 计算量加权批发成本,根据专利地位,配方和治疗类别分析价格趋势.
- 使用回归分析和事件研究来评估价格与竞争之间的关系,特别是独家权后的损失.
主要成果:
- 在研究期间,品牌抗癌药物价格普遍上,而仿制药和生物类似药的价格下降.
- 在失去市场独家权后,仿制药和生物类似药的价格下降,而品牌价格保持相对稳定.
- 事件研究显示,独家权到期后的价格趋势各不相同,这表明了复杂的市场动态.
结论:
- 市场竞争,特别是通过仿制药和生物类似药的可用性,可以提高支付者和患者的抗癌药物的负担能力.
- 由于大量抗癌药物的仿制药和生物类似药的可用性有限,竞争的积极影响目前是有限的.
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