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Updated: Jun 6, 2025

Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs
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Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs

Published on: May 15, 2019

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埃洛图祖马布与波马利多米德,博尔特佐米布和德克萨米松联合使用,用于复发性和耐火性多发性骨髓瘤

Andrew J Yee1,2, Jacob P Laubach3,2, Erica L Campagnaro4

  • 1Center for Multiple Myeloma, Massachusetts General Hospital Cancer Center, Boston, MA.

Blood advances
|December 3, 2024
PubMed
概括

将埃洛图祖马布添加到波马利多米德,博尔特佐米布和德克萨米他 (elo-PVd) 中,对复发性/耐药性多发性骨髓瘤 (MM) 显示出有希望. 这种四重治疗方案在重度预治疗的患者中实现了56.3%的整体应答率.

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