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Updated: Jun 6, 2025

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通过ICOSL抑制T毛囊辅助细胞来减轻原蛋白诱导的关节炎

Fei-Fei Huo1, Xue-Yang Zou1, Yi Zhang1

  • 1Department of Intensive Care Medicine, The First Hospital of Jilin University, Department of Immunology, College of Basic Medical Sciences. Clinical Laboratory, The First Hospital of Jilin University, Changchun, China.

International immunopharmacology
|December 3, 2024
PubMed
概括

在类风湿性关节炎 (RA) 患者中,自身免疫调节剂 (Aire) 降低. 下方Aire抑制诱导性共刺激分子接体 (ICOSL),减少T毛囊辅助细胞 (Tfh) 和自身抗体的产生,可能缓解RA症状.

关键词:
自身免疫调节器 (Aire) 的作用树突细胞 (DCs) 是指树突细胞.诱导性辅助刺激分子连接物 (ICOSL)类风湿性关节炎 (RA) 是一种毛囊T辅助细胞 (Tfh) 是一种细胞.

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