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揭示了肝细胞SATB1与自身免疫性肝炎中的先天免疫之间的相互作用

Shuhui Wang1, Zheng Huang2, Shangshu Nie1

  • 1Department of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, China.

International immunopharmacology
|December 3, 2024
PubMed
概括

在自身免疫性肝炎 (AIH) 期间,SATB1在肝细胞上调,通过增加CCL2和吸引炎症性巨细胞,促进肝损伤. 抑制SATB1可能为AIH提供治疗策略.

关键词:
自体免疫性肝炎是一种自身免疫性肝炎.在CCL2中,我们可以使用CCL2.单细胞衍生的巨细胞.在SATB1中,SATB1是SATB1.转录法规 转录法规

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