关于初级保健中抗菌药物管理的拟议宏观质量指标:一项观察性研究
C Slekovec1, E Pouly2, L Malinowski3
1Hospital hygiene department, Besancon University Hospital, Besancon, France; UMR 6249 Chrono-environnement, University of Bourgogne Franche Comté, Besançon, France.
Infectious diseases now
|December 3, 2024
概括
宏观质量指标有效指导常见感染的抗生素管理. 这些从抗生素使用数据中得出的简单指标有助于针对干预措施,即使在总体消费低的地区也是如此.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 药物经济学 药物经济学
背景情况:
- 抗生素管理对于打击抗菌素耐药性至关重要.
- 有效的策略需要可靠的指标来监测抗生素使用.
- 宏观质量指标为评估抗生素处方模式提供了一种简化方法.
研究的目的:
- 评估两种宏观质量指标在指导抗生素管理中的有用性.
- 评估指标识别改善社区常见感染抗生素处方的目标的能力.
主要方法:
- 在Bourgogne-Franche-Comté地区从2015年至2020年使用的抗生素补偿数据 (定义的每日剂量).
- 在15-64岁的女性中计算出尿路感染指标 (斯福米 + 尼托福兰 + 皮夫梅西林) / (西普罗夫洛克萨 + 奥洛克萨 + 诺夫洛克萨)
- 在15岁以下的儿童中计算了耳朵,鼻子,喉和呼吸道感染 (阿莫西西林) / (阿莫西西林-克拉夫兰酸+口服3GC) 的指标.
主要成果:
- 全球抗生素消费量因部门而异 (2020年每1000名居民/天2.22.226.6 DDD).
- 最低的指标得分是在尼弗尔和约恩观察到的.
- 随着时间的推移,这两项指标都普遍增加,但2020年因尼特洛黄因短缺而导致的尿路感染指标是个明显的例外.
结论:
- 宏观质量指标有效地识别了针对流行社区感染的抗生素管理目标.
- 这些指标可以很容易地从定量数据计算出来,独立于诊断信息.
- 它们为全科医生提供了针对人口,分子和诊断考虑的有针对性的见解.
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