生存结果和手术拒绝的差异对于乳腺甲状腺癌的乳腺甲状腺癌
Jade C Bowers1, Bansi P Savaliya2, Swathi R Raikot2
1College of Medicine, Florida State University, Tallahassee, FL, U.S.A.; jb23e@med.fsu.edu.
Anticancer research
|December 3, 2024
概括
在乳头甲状腺癌 (PTC) 患者中,拒绝手术与更糟糕的生存率有关. 诸如老年和社会经济劣势等因素影响了这一决定,突出了针对性干预的必要性.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 健康差异 在健康上的差异
背景情况:
- 手术是乳头甲状腺癌 (PTC) 的首要治疗方法.
- 患者拒绝推的手术可能会对生存结果产生负面影响.
- 了解拒绝手术背后的因素对于改善患者护理和治疗坚持至关重要.
研究的目的:
- 为了评估手术拒绝对乳头甲状腺癌 (PTC) 患者整体生存期 (OS) 的影响.
- 确定与PTC患者拒绝手术相关的人口和临床因素.
主要方法:
- 使用国家癌症数据库 (2004-2019) 进行回顾性队列研究.
- 使用卡普兰-梅尔法和日志等级测试,分析整体存活 (OS).
- 使用奇平方和威尔科克森排列和值测试对患者特征的评估.
主要成果:
- 只有0.2%的PTC患者拒绝手术;然而,拒绝与明显较低的OS率 (1年:87%vs96%;5年:34%vs56%).
- 拒绝手术的患者年龄较大,更频繁的男性,不成比例地代表了少数民族,低收入和没有保险的人口.
- 在手术拒绝率 (p<0.001) 中观察到显著的人口和社会经济差异.
结论:
- 在PTC中拒绝手术与较差的整体存活率有关.
- 老年人,社会经济弱势群体和种族/民族少数群体更有可能拒绝手术.
- 解决患者担忧和障碍的干预措施对于改善治疗接受率和生存率至关重要.
相关概念视频
01:21Cancer Survival Analysis
328
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
328
01:30Psychosurgery
46
Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
46