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Updated: Jun 6, 2025

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聚合物基础的多层微囊的形状对细胞内部化的影响

Xiaoqiang Zhang1,2,3, Jianmei Han2, Ting Ding1

  • 1Joint Research Centre on Medicine, Xiangshan Hospital of Wenzhou Medical University, Ningbo, Zhejiang 315700, China.

Langmuir : the ACS journal of surfaces and colloids
|December 3, 2024
PubMed
概括

微囊的形状显著影响细胞吸收. 头和立方形状显示了比球形更高的内化率,为药物载体的发展提供了洞察力.

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相关概念视频

Cellular Membranes and Drug Transport01:24

Cellular Membranes and Drug Transport

Drugs must traverse multiple biological barriers, such as multi-layered skin, single-layered intestinal epithelium, and the plasma membrane, to reach their target sites within the body. The plasma membrane, a highly structured composite of phospholipids, carbohydrates, and proteins, is the cell's protective boundary, facilitating selective substance exchange.
Phospholipids arrange themselves into a bilayer, with hydrophilic heads oriented outward and hydrophobic tails facing inward.
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