牙周病和妊娠期糖尿病之间的关联:系统性审查和元分析
Juan Manuel García-Martos1, Francisco Javier Valverde-Bolívar2, María Teresa Campillo-López3
1Medical Clinic Bulevar, Health district Jaen, south Jaen, Jaen, Spain.
Primary care diabetes
|December 3, 2024
概括
牙周病 (PD) 显著增加了孕妇患妊娠糖尿病 (GDM) 的风险. 口腔健康计划对于改善母亲的代谢控制和减少并发症至关重要.
科学领域:
- 产科和妇科 产科和妇科
- 牙周病学 牙周病学
- 内分泌学 在内分泌学.
背景情况:
- 牙周病 (PD) 与不良妊娠结果有关.
- 患PD可能会加剧胰岛素抵抗,胰岛素抵抗是妊娠糖尿病 (GDM) 的关键因素.
研究的目的:
- 系统地审查和元分析牙周病与患妊娠糖尿病的风险之间的关联.
主要方法:
- 在互联网数据库中进行了系统的文献搜索.
- 11项涉及2032名孕妇的研究被纳入了元分析.
- 几率比率 (OR) 和置信区间 (CI) 用固定和随机效应模型计算,以埃格尔测试和漏斗图进行偏差评估.
主要成果:
- 牙周病被确定为GDM的重要危险因素.
- 在患有PD的女性中,GDM的整体OR为1.83 (95% CI 1.25-2.69,p<0.0017).
- 调整后的OR也证实了PD作为一个危险因素 (OR=1.83,95% CI 1.31-2.56,p<0.004).
结论:
- 牙周病对患有妊娠期糖尿病的风险很高.
- 为计划怀孕的妇女实施口腔健康计划对于更好的代谢控制和减少产科并发症至关重要.
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