相关实验视频
Updated: Jun 6, 2025

08:46
A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
Published on: August 12, 2020
6.3K
早发性败血症:临床观察或风险因素方法?
Sofia Romay Oliveira1, Cintia Lopes1, Alana Beatriz Coelho Basilio1
1Universidade Federal do Paraná (UFPR), Complexo Hospital de Clínicas, Unidade Materno Infantil - Alojamento Conjunto e Centro Cirúrgico Obstétrico, Curitiba, Paraná, Brazil.
Jornal de pediatria
|December 3, 2024
概括
新生儿早期性败血症 (EOS) 的临床观察方法与围产期危险因素方法相比,减少了实验室检测和抗生素使用,而不影响EOS发病率. 对于最佳的新生儿评估策略,需要进一步的研究.
科学领域:
- 新生儿医学 新生儿医学
- 儿童传染病 儿童传染病
- 临床实践指南 临床实践指南
背景情况:
- 早期发作的败血症 (EOS) 是一个关键的新生儿问题.
- 目前的诊断方法包括风险分层和临床观察.
- 优化诊断策略可以减少不必要的干预.
研究的目的:
- 为了比较临床观察方法与围产期危险因素方法来管理新生儿早期发作的败血症.
- 评估每个方法对实验室检测,抗生素使用和EOS发病率的影响.
主要方法:
- 从2021年11月到2022年3月,对1086名新生儿 (妊娠≥34周) 进行了回顾性观察研究.
- 从产前护理,分娩,住院和实验室测试中评估临床数据.
- 两种方法之间的传染性查率和经验性抗生素治疗的比较.
主要成果:
- 临床观察方法导致感染查减少了65.2%,而围产期风险因素方法则减少了8.9%和26.5%.
- 经验性抗生素治疗EOS的临床观察方法减少了37.1% (2.0%对3.2%).
- 在这两种方法之间,在培养确认的EOS发生率上没有发现显著差异.
结论:
- 临床观察方法与新生儿怀疑EOS的实验室检测和抗生素使用减少有关.
- 这种方法并没有对培养证实EOS的发病率产生负面影响.
- 需要进一步的研究来完善新生儿检查协议,并确定最佳的EOS预测因子.
相关概念视频
Healthcare Associated Infections II: Preventive Measures
2.5K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.5K
Infection
7.7K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
7.7K
Steps in Outbreak Investigation
106
In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
106
Factors Affecting the Risk of Infection
11.4K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.4K
Pneumonia I: Introduction
211
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
211
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
4.0K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
4.0K

