胃食道逆流性疾病和耳之间的关联在全国基于人口的队列研究中
Sung-Woo Kang1, Min Ho An2,3, Seojung Ha4
1Department of Internal Medicine, Kyung Hee University College of Korean Medicine, Seoul, 02447, Korea.
Scientific reports
|December 3, 2024
概括
胃食道逆流性疾病 (GERD) 与耳有关,可能是由于影响内耳的酸逆流引起的. 然而,质子抑制剂药物并没有显著减少GERD患者的耳发作.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 胃肠病学 胃肠病学
- 流行病学 流行病学
背景情况:
- 胃食道逆流性疾病 (GERD) 涉及胃部内容的反.
- 酸性反流可能会通过欧斯塔基管影响中耳和内耳的平静.
- GERD和耳之间存在潜在的联系需要进行调查.
研究的目的:
- 为了调查GERD和耳之间的关联.
- 探索酸性反流在耳发育中的作用.
主要方法:
- 追溯的队列研究.
- 利用来自韩国国家医疗保险服务-国家样本队列 (2012-2019) 的669,159名患者的数据.
主要成果:
- 在GERD和耳之间发现了显著的关联.
- 在GERD患者中使用质子抑制剂并没有显著减少耳发作.
结论:
- GERD与耳有很高的相关性.
- 目前用于GERD的质子抑制剂治疗可能无法预防耳发育.
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