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Updated: Jun 5, 2025

Generation and Culturing of Primary Human Keratinocytes from Adult Skin
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角质细胞的失调驱动了全身性红斑狼的发病

Jingru Tian1,2,3,4, Liqing Shi1,2,3, Dingyao Zhang5

  • 1Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China.

Cellular & molecular immunology
|December 3, 2024
PubMed
概括

系统性红斑狼 (SLE) 可能从皮肤细胞开始,而不是免疫细胞. кератино细胞中减少的PPARγ触发了一连串,导致SLE在一个新的小鼠模型中发展.

关键词:
树突性细胞 树突性细胞干扰素调节因子3 3角质细胞 (keratinocytes) 是一种细胞.过氧体增殖器激活的受体玛受体.系统性红血性狼 (Systemic lupus erythematosusus) 是一种全身性狼.这是一种I型干扰子.

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