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味觉感知和唾液成分在燃烧口腔综合征中没有改变
Marina Kolkka1, Satu Jääskeläinen2, Heli Forssell3
1Department of Oral and Maxillofacial Diseases, Turku University Hospital, Turku, Finland.
Oral diseases
|December 4, 2024
概括
与对照组相比,燃烧口腔综合征 (BMS) 患者在口味感知或唾液中没有差异. 只有BMS患者报告金属味道,这表明需要进一步研究.
科学领域:
- 口腔医学是指口腔医学.
- 感官科学 感官科学
- 生物化学 生物化学
背景情况:
- 燃烧口腔综合征 (BMS) 是一种复杂的口腔疾病,通常与改变的味道和唾液功能有关.
- 了解味觉和唾液组成之间的相互作用对于管理BMS至关重要.
研究的目的:
- 为了研究口腔炎综合征 (BMS),口味感知和唾液特征之间的关系.
- 为了比较BMS患者的味觉和唾液参数与健康对照.
主要方法:
- 在31名BMS患者和20名对照人群中,使用味道条和全口评价来评估味觉感知.
- 刺激的唾液被收集,以测量流量,pH值,电解质,MUC5B,MUC7,脱水氨 (DHEA) 和总蛋白质.
主要成果:
- 在BMS患者和对照人群之间,没有观察到味道模式,唾液流速或唾液成分的显著差异.
- 在这两组人中,唾液成分和味道之间存在微弱的关联.
- 金属味道幻象仅由BMS患者报告 (p=0.03).
结论:
- 与之前的一些研究相反,与对照组相比,BMS患者没有表现出改变的味觉或唾液变量.
- 唾液参数和味道评分之间的弱相关性在两组中都是相似的.
- 建议进行更大规模的研究,以验证这些发现在燃烧口腔综合征研究中的有效性.
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